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Deprived of phase 4 &/or REM sleep, your joints will get tender, without having arthritic symptoms The brand-name drugs are much more expensive than their generics. If muscle aches occur, a lower dose should be tried. In that stage, your norepinephrine and dopamine are thought to "reconstitute", according to Dr. 6k views Answered >2 years ago Merged Thank. A generic drug is an exact copy of the active drug in a brand-name. Both Lipitor and Zocor are good for lowering LDL, but Zocor is better at increasing HDL and tends to have fewer gastrointestinal side effects, according to one study. Both of these drugs have a number of adverse effects, which may cause some patients to hesitate before agreeing to. 7 out of 10 from a total of 101 ratings on Drugs. Zocor (simvastatin) is a good medication to improve your cholesterol. There is some difference in the incidence of side effects but clinically these are not seen very often. But either can cause muscle aches (in up to 10% of people) which is dependent on the dose. Deprived of phase 4 &/or REM sleep, your joints will get tender, without having arthritic symptoms Lipitor ( atorvastatin) and Vytorin ( simvastatin and ezetimibe) are used to lower cholesterol levels in the blood. At the time, the trycyclics were the best way to get a patient into the heaviest phase of sleep : phase 4 & REM. That means both drugs target the same mechanism to lower bad (LDL) cholesterol—binding up HMG-CoA reductase in the liver’s cholesterol production cycle Very similar: Atorvastatin ( lipitor) is a little more potent, milligram for milligram than Simvastatin ( zocor ). While the former drug is also available as a generic, the latter is not. Simvastatin is the generic name of the brand compound Zocor. 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